Wuhan Fine Biotech Co., Ltd.'s PRKACB antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, Precipitation, ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot. The PRKACB antibody was generated using PRKACB as the antigen and it reacts with Homo Sapiens, Human, Mouse, and Rat.
Description
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis